Composition:
1 tablet contains: active ingredient: 500 mg L-glutathione reductive Setria; licorice root extract (Glycyrrhiza glabra) 278 mg (equivalent to 50.04 mg glycyrrhizic acid);
Ingredients: L-glutathione reductive Setria; licorice root extract; filler: microcrystalline cellulose, dicalcium phosphate; coating: shellac, acetic acid esters of mono- and diglycerides of fatty acids, polyvinylpyrrolidone; anti-caking agent: silicon dioxide, magnesium salts of fatty acids, hydroxypropyl methylcellulose.
Method of application and recommended daily dose:
Take 1 tablet per day with sufficient liquid as an additional source of biologically active components:
L-glutathione to restore the level of L-glutathione, an antioxidant that supports the detoxification function by protecting the body's cells from excessive exposure to free oxygen radicals;
Glycyrrhizic acid, which has natural anti-inflammatory properties.
The duration of consumption is determined by the doctor individually.
Properties of the main components:
Setria is a patented form of reduced L-glutathione, produced by biofermentation, which can increase the body's own glutathione levels. (*1)
The reduced form of L-glutathione (GSH) is a biologically active form.
Glutathione is an antioxidant and plays a role in the detoxification of drugs and xenobiotics. The main function of glutathione is to protect the body's cells from oxidative stress and toxins.
L-glutathione Setria may have an effect on the immune system: in a clinical study, it demonstrated the ability to stimulate T-lymphocyte proliferation and increase the cytotoxicity of blood NK cells by two times from the baseline level after 3 months of administration at a dose of 1000 mg/day (*2).
*In a pilot clinical study, L-glutathione demonstrated potential therapeutic effects in patients with non-alcoholic fatty liver disease (*3).
Glyceric acid acts similarly to corticosteroid hormones, exhibiting:
anti-inflammatory effects (associated with the ability to stimulate the synthesis of anti-inflammatory cytokines: interleukins (IL)-IL-2, IL-10, IL-12 and suppressing the expression of pro-inflammatory cytokines: IL-8, IL-1β, tumor necrosis factor α) (*4);
antiviral effect (associated with the induction of interferon formation). Active against DNA and RNA viruses, including various strains of Herpes simplex, Varicella zoster, human papillomavirus, and cytomegalovirus; (*5)
antifibrotic effect (explained by the predominant effect on collagen production by stellate liver cells and the destruction of activated Ito cells with the participation of natural killer cells); (*6)
anticarcinogenic effect (associated with the ability to increase the concentration of cytochrome P450 (CYP) in the liver) (*5)

Precautions for use:
Do not use: if you are hypersensitive to any of the product's ingredients (see “Ingredients” section), if you are pregnant or breastfeeding, or if you are a child. Do not exceed the recommended daily dose.
Dietary supplements should not be considered a substitute for a varied and balanced diet and a healthy lifestyle.
Form of release:
10 tablets in a blister pack. 3 blister packs in a cardboard box.
Storage conditions:
Store in a dry and cool place, away from heat sources. The expiration date applies to a product in which the blister pack has not been damaged and has been stored properly.
Keep out of reach of children under 3 years of age.
Dietary supplement. Not a medicine.
Gluten- and lactose-free.
Expiration date:
indicated on the packaging.
Manufacturer:
Setria ® is a registered trademark of KYOWA HAKKO BIO CO. (Japan).
Tabletting and packaging carried out in Italy by FMC S.R.L.. VIA CASILINA SUD 69 E 03013 FERENTINO (FR). Italy on behalf of VITASAIN SARL, 52 Rue Saint-André des Arts 75006 Paris, France.
Manufactured in accordance with GMP (Good Manufacturing Practice) standards, which guarantee that the product is manufactured and controlled in accordance with quality standards, in accordance with the marketing authorization, and is fit for its intended purpose.
Importer (company that handles consumer complaints):
VITASAN-UKRAINE LLC, legal address: 01042, Kyiv, Ukraine, Pecherskyi district, NOVOPECHERSKYI LANE, building 18, office 32. Tel +380673801918
Sources of information.
(*1)Randomized Controlled Trial Eur J Nutr/2015 Mar;54(2):251-63. doi: 10.1007/s00394-014-0706-z. Epub 2014 May 5.
(*2) https://setriaglutathione.com/en/setria-glutathione-infographic
(*3) https://pmc.ncbi.nlm.nih.gov/articles/PMC5549431/
(*4) https://pubmed.ncbi.nlm.nih.gov/33505216/
https://pmc.ncbi.nlm.nih.gov/articles/PMC10744776/
(6)https://www.sciencedirect.com/science/article/abs/pii/S0944711322006754
https://pmc.ncbi.nlm.nih.gov/articles/PMC4052927/

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